Robust TDT-type candidate-gene association tests
نویسندگان
چکیده
منابع مشابه
Obtaining Robust Tdt-type Candidate-gene Association Tests for a Family of Genetic Models
Introduction The transmission disequilibrium test (TDT) of Spielman et al. (1993) was developed as test of linkage between a marker locus and a disease in the presence of allelic association and can also be used in testing for association between a candidate gene and a disease. By focusing on a specific genetic model in the candidate gene setting more powerful tests can be obtained. Schaid and ...
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ژورنال
عنوان ژورنال: Annals of Human Genetics
سال: 2002
ISSN: 0003-4800,1469-1809
DOI: 10.1046/j.1469-1809.2002.00104.x